3. Sudden Severe Big-Toe Pain Warmth, redness, and swelling in your big toe? You may have gout . Research shows this type of arthritis — which inflames the joint in the base of your big toe, causing intense pain — is on the rise, especially in men.e60dc2a1-f33c-4a05-9b50-8e3e8e597629830da214-5fb3-448a-a79b-b933f46ba417 “The classic symptom is having to put your foot outside the sheet because even the sheet lying on it hurts,” Dr. Granberry says. Gout is sometimes called “the…